{"id":2762,"date":"2020-04-15T11:33:16","date_gmt":"2020-04-15T11:33:16","guid":{"rendered":"https:\/\/researchreproduction.gr\/site\/?p=2762"},"modified":"2020-04-15T11:35:34","modified_gmt":"2020-04-15T11:35:34","slug":"demographic-clinical-and-hormonal-characteristics-of-patients-with-premature-ovarian-insufficiency-and-those-of-early-menopause-data-from-two-tertiary-premature-ovarian-insufficiency-centers-in-gree","status":"publish","type":"post","link":"https:\/\/researchreproduction.gr\/site\/?p=2762","title":{"rendered":"Demographic, clinical and hormonal characteristics of patients with premature ovarian insufficiency and those of early menopause: data from two tertiary premature ovarian insufficiency centers in Greece"},"content":{"rendered":"<p>[:EL]<\/p>\n<div class=\"hlFld-Abstract test\">\n<div class=\"sectionInfo abstractSectionHeading\">\n<div>\n<p>Maria Sotiria Bompoula, Georgios Valsamakis, Spyridoula Neofytou, Pantelis Messaropoulos, Nikolaos Salakos, George Mastorakos &amp; Sophia N. Kalantaridou<\/p>\n<\/div>\n<div class=\"sectionHeading\"><strong>Abstract<\/strong><\/div>\n<\/div>\n<div class=\"abstractSection abstractInFull\">\n<p>&nbsp;<\/p>\n<p>The aim of the study was to compare demographic, hormonal and clinical parameters in patients with premature ovarian insufficiency (POI) and women with early menopause in Greece. One hundred thirty-nine women of Greek origin, aged 14\u201345 years, referring for oligomenorrhea and having elevated FSH concentrations were divided into three groups regarding the age of menstrual disturbances onset [POI<sub>1<\/sub>: &lt;\/=30 years (<i>n<\/i>\u2009=\u200942); POI<sub>2<\/sub>: 31\u201339 years (<i>n<\/i>\u2009=\u200936); early menopause: 40\u201345 years (<i>n<\/i>\u2009=\u200961)].<\/p>\n<p>The mean age of menstrual disturbances onset and that of diagnosis in all POI and early menopause patients were 28.7 years (28.7\u2009\u00b1\u20097.7) versus 42.1 years (42.1\u2009\u00b1\u20091.5) and 33.8 years (33.8\u2009\u00b1\u20097.2) versus 43.3 years (43.3\u2009\u00b1\u20091.4), respectively. POI patients and women with early menopause were diagnosed, respectively, five years and approximately four to six months later than the age of menstrual disturbances onset. Moreover, FSH<sub>2<\/sub> (second confirmatory FSH measurement at 4-to-6-weeks interval) was greater in all POI patients than in early menopause women (55.4\u2009\u00b1\u200933.9 vs. 32.4\u2009\u00b1\u200919.4; <i>p<\/i>\u2009&lt;\u2009.05) whereas mean age of menarche was greater in early menopause women than in POI patients (13\u2009\u00b1\u20091.3 vs. 12\u2009\u00b1\u20092.2; <i>p<\/i>\u2009&lt;\u2009.05). Furthermore, FSH<sub>2<\/sub> was increased in all POI and decreased in early menopause patients.<\/p>\n<\/div>\n<\/div>\n<div class=\"abstractKeywords\">\n<div class=\"hlFld-KeywordText\">Keywords: Premature ovarian insufficiency<span class=\"comma\">,\u00a0<\/span>premature ovarian failure<span class=\"comma\">,\u00a0<\/span>hypoestrogenism<span class=\"comma\">,\u00a0<\/span>subfertility<span class=\"comma\">,\u00a0<\/span>early menopause<\/div>\n<div><a href=\"https:\/\/doi.org\/10.1080\/09513590.2020.1739266\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/doi.org\/10.1080\/09513590.2020.1739266<\/a><\/div>\n<\/div>\n<p>[:en]<\/p>\n<div class=\"hlFld-Abstract test\">\n<div class=\"sectionInfo abstractSectionHeading\">\n<div>\n<p>Maria Sotiria Bompoula, Georgios Valsamakis, Spyridoula Neofytou, Pantelis Messaropoulos, Nikolaos Salakos, George Mastorakos &amp; Sophia N. Kalantaridou<\/p>\n<\/div>\n<div class=\"sectionHeading\"><strong>Abstract<\/strong><\/div>\n<\/div>\n<div class=\"abstractSection abstractInFull\">\n<p>&nbsp;<\/p>\n<p>The aim of the study was to compare demographic, hormonal and clinical parameters in patients with premature ovarian insufficiency (POI) and women with early menopause in Greece. One hundred thirty-nine women of Greek origin, aged 14\u201345 years, referring for oligomenorrhea and having elevated FSH concentrations were divided into three groups regarding the age of menstrual disturbances onset [POI<sub>1<\/sub>: &lt;\/=30 years (<i>n<\/i>\u2009=\u200942); POI<sub>2<\/sub>: 31\u201339 years (<i>n<\/i>\u2009=\u200936); early menopause: 40\u201345 years (<i>n<\/i>\u2009=\u200961)].<\/p>\n<p>The mean age of menstrual disturbances onset and that of diagnosis in all POI and early menopause patients were 28.7 years (28.7\u2009\u00b1\u20097.7) versus 42.1 years (42.1\u2009\u00b1\u20091.5) and 33.8 years (33.8\u2009\u00b1\u20097.2) versus 43.3 years (43.3\u2009\u00b1\u20091.4), respectively. POI patients and women with early menopause were diagnosed, respectively, five years and approximately four to six months later than the age of menstrual disturbances onset. Moreover, FSH<sub>2<\/sub> (second confirmatory FSH measurement at 4-to-6-weeks interval) was greater in all POI patients than in early menopause women (55.4\u2009\u00b1\u200933.9 vs. 32.4\u2009\u00b1\u200919.4; <i>p<\/i>\u2009&lt;\u2009.05) whereas mean age of menarche was greater in early menopause women than in POI patients (13\u2009\u00b1\u20091.3 vs. 12\u2009\u00b1\u20092.2; <i>p<\/i>\u2009&lt;\u2009.05). Furthermore, FSH<sub>2<\/sub> was increased in all POI and decreased in early menopause patients.<\/p>\n<\/div>\n<\/div>\n<div class=\"abstractKeywords\">\n<div class=\"hlFld-KeywordText\">Keywords: Premature ovarian insufficiency<span class=\"comma\">, <\/span>premature ovarian failure<span class=\"comma\">, <\/span>hypoestrogenism<span class=\"comma\">, <\/span>subfertility<span class=\"comma\">, <\/span>early menopause<\/div>\n<div><a href=\"https:\/\/doi.org\/10.1080\/09513590.2020.1739266\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/doi.org\/10.1080\/09513590.2020.1739266<\/a><\/div>\n<\/div>\n<p>[:]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[:EL] Maria Sotiria Bompoula, Georgios Valsamakis, Spyridoula Neofytou, Pantelis Messaropoulos, Nikolaos Salakos, George Mastorakos &amp; Sophia N. Kalantaridou Abstract &nbsp; The aim of the study was to compare demographic, hormonal and clinical parameters in patients with<a class=\"moretag\" href=\"https:\/\/researchreproduction.gr\/site\/?p=2762\">Read More&#8230;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-2762","post","type-post","status-publish","format-standard","hentry","category-5"],"_links":{"self":[{"href":"https:\/\/researchreproduction.gr\/site\/index.php?rest_route=\/wp\/v2\/posts\/2762","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/researchreproduction.gr\/site\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/researchreproduction.gr\/site\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/researchreproduction.gr\/site\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/researchreproduction.gr\/site\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2762"}],"version-history":[{"count":3,"href":"https:\/\/researchreproduction.gr\/site\/index.php?rest_route=\/wp\/v2\/posts\/2762\/revisions"}],"predecessor-version":[{"id":2765,"href":"https:\/\/researchreproduction.gr\/site\/index.php?rest_route=\/wp\/v2\/posts\/2762\/revisions\/2765"}],"wp:attachment":[{"href":"https:\/\/researchreproduction.gr\/site\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2762"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/researchreproduction.gr\/site\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2762"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/researchreproduction.gr\/site\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2762"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}